Digitalis after AMI.

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Digitalis after AMI.

Clearly eq (5) is analytically equivalent to eq (4). When implemented on computers of adequate precision, the relationships used by Shell and our group also lead to numerically equivalent results. Shell states that the correlation (r) between histologic and en-zymatic estimates can be improved from .2 to .5 by adjusting for control enzyme levels (regression between columns 1 and 2 in Shell's le...

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Digitalis-associated cardiac mortality after myocardial infarction.

The effect of digitalis therapy on 4-month posthospital cardiac mortality was investigated in 812 patients who survived the hospital phase of acute myocardial infraction. A stepwise multiple logistic regression analysis was used to identify variables associated with increased mortality and to adjust for differences in confounding variables between digitalis and nondigitalis patients. The major ...

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Digitalis.

Cardiac glycosides have played a prominent role in the therapy of congestive heart failure since William Withering codified their use in his late 18th century monograph on the efficacy of the leaves of the common foxglove plant (Digitalis purpurea). Despite their widespread acceptance into medical practice in the ensuing 200 years, both the efficacy and the safety of this class of drugs continu...

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Clinical pacing post-conditioning during revascularization after AMI.

Intermittent dyssynchrony, induced by ventricular pacing, during early reperfusion reduces infarct size in pre-clinical studies. We evaluated cardioprotection by pacing post-conditioning (PPC) in ST-segment elevation myocardial infarction in a randomized, controlled, single-center, single-blinded, first-in-man study. Patients with first ST-segment elevation myocardial infarction received either...

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Statin trials and goals of cholesterol-lowering therapy after AMI.

Several randomized clinical trials using statins in the prevention of coronary heart disease (CHD) have demonstrated benefit, both in terms of retardation of the progression of signs of coronary atherosclerosis and in reduced morbidity and mortality rates. Three of these trials have examined the long-term effect of statins in patients with previous myocardial infarction. The Scandinavian Simvas...

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ژورنال

عنوان ژورنال: Circulation

سال: 1977

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.56.5.898